Research Article

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

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Science  20 Apr 2018:
Vol. 360, Issue 6386, eaaq1392
DOI: 10.1126/science.aaq1392

Article Information

vol. 360 no. 6386

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History: 
  • Received for publication October 5, 2017
  • Accepted for publication February 19, 2018

Author Information

  1. Tsung-Li Liu1,*,
  2. Srigokul Upadhyayula1,2,3,4,*,
  3. Daniel E. Milkie1,
  4. Ved Singh1,
  5. Kai Wang1,,
  6. Ian A. Swinburne5,
  7. Kishore R. Mosaliganti5,
  8. Zach M. Collins5,
  9. Tom W. Hiscock5,
  10. Jamien Shea1,
  11. Abraham Q. Kohrman6,
  12. Taylor N. Medwig6,
  13. Daphne Dambournet7,
  14. Ryan Forster7,
  15. Brian Cunniff2,3,,
  16. Yuan Ruan8,
  17. Hanako Yashiro8,
  18. Steffen Scholpp9,10,
  19. Elliot M. Meyerowitz8,
  20. Dirk Hockemeyer7,
  21. David G. Drubin7,
  22. Benjamin L. Martin6,
  23. David Q. Matus6,
  24. Minoru Koyama1,
  25. Sean G. Megason5,
  26. Tom Kirchhausen1,2,3,4,
  27. Eric Betzig1,§
  1. 1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
  2. 2Department of Cell Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
  3. 3Program in Cellular and Molecular Medicine, Boston Children’s Hospital, 200 Longwood Avenue, Boston, MA 02115, USA.
  4. 4Department of Pediatrics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
  5. 5Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
  6. 6Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.
  7. 7Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
  8. 8Howard Hughes Medical Institute and Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  9. 9Living Systems Institute, College of Life and Environmental Sciences, University of Exeter, Exeter EX4 4QD, UK.
  10. 10Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, 76021 Karlsruhe, Germany.
  1. §Corresponding author. Email: betzige{at}janelia.hhmi.org
  1. * These authors contributed equally to this work.

  • Present address: Institute of Neuroscience, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, China.

  • Present address: Department of Pathology, University of Vermont College of Medicine, Burlington, VT 05401, USA.

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Apr 201849600858410798
May 20181692221362967
Jun 201837027911090
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Sep 20181016785389
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