Staving off diabetes

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Science  27 Apr 2018:
Vol. 360, Issue 6387, pp. 394
DOI: 10.1126/science.360.6387.394-c

Childhood obesity is a growing epidemic associated with increased risk of health issues later in life. Bjerregaard et al. asked whether, and at what age, shedding of excess pounds by overweight kids influenced their chance of developing type 2 diabetes as adults. The authors examined more than 62,000 Danish men for whom height and weight data were available from childhood into early adulthood. Individuals who were overweight throughout adolescence were four times as likely to develop adult type 2 diabetes. However, males who lost excess weight by age 13 cut their diabetes risk to that of those who were never overweight. Thus, maintaining a healthy body mass index throughout adolescence should reduce future chances of type 2 diabetes in men.

N. Engl. J. Med. 10.1056/NEJMoa171323.1 (2018).

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