Research Article

Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis

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Science  11 May 2018:
Vol. 360, Issue 6389, eaan5780
DOI: 10.1126/science.aan5780

Article Information

vol. 360 no. 6389

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History: 
  • Received for publication May 3, 2017
  • Resubmitted December 14, 2017
  • Accepted for publication March 16, 2018

Author Information

  1. Keun Woo Ryu1,2,3,
  2. Tulip Nandu1,2,
  3. Jiyeon Kim4,
  4. Sridevi Challa1,2,
  5. Ralph J. DeBerardinis4,5,6,
  6. W. Lee Kraus1,2,3,*
  1. 1Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Division of Basic Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Program in Genetics, Development, and Disease, Graduate School of Biomedical Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Children’s Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  5. 5Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  6. 6McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. *Corresponding author. Email: lee.kraus{at}utsouthwestern.edu

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