Books et al.Heredity

Beyond epigenetics

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Science  29 Jun 2018:
Vol. 360, Issue 6396, pp. 1408
DOI: 10.1126/science.aau1392

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In many complex animals, the germ line is separated from the rest of the body early in development, which led the 19th century biologist August Weismann to conclude that environmentally caused changes in an organism are not inherited. A revelation in recent years, and the focus of Russell Bonduriansky and Troy Day's admirable book, Extended Heredity, is the finding that "Weismann's barrier" is remarkably porous, with epigenetics representing "only the tip of the iceberg."