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Science  27 Jul 2018:
Vol. 361, Issue 6400, pp. 417
DOI: 10.1126/science.361.6400.417

Clinical Analyzer

Thermo Fisher Scientific's Cascadion SM Clinical Analyzer brings together the ease of use of clinical analyzers with the selectivity and sensitivity of liquid chromatography-tandem mass spectrometry (LC-MS/MS). The fully automated analyzer is designed for use in a variety of settings, including hospital laboratories, and can provide results for a range of clinical tests. It is a turnkey solution that enables clinical labs to easily adopt the power and capabilities of LC-MS/MS as the gold standard in screening and diagnostic testing. The Cascadion system combines assays, software, accessories, consumables, and support/service in a standalone system designed to meet the regulatory requirements for routine and specialized clinical testing. 

RNA Purification Kit

The FastGene Premium RNA kit is developed for rapid, efficient, and clean purification of RNA from tissues and cells for challenging applications such as next-generation sequencing. The kit's silica-based technology dispenses with phenols in favor of superior deoxyribonuclease treatment to ensure the near-complete elimination of genomic DNA. It is the only RNA purification kit available that uses three separate column technologies. This results in extracted RNA of the highest concentration and purity—free from contaminating nucleic acids, proteins, and other biomolecules.

Laboratory Bottles

BrandTech Scientific is pleased to introduce VITgrip laboratory bottles from VITLAB. VITgrip bottles are optimized for storage and sample collection. They are built with an ergonomic slim waist design to aid in handling, double-sided graduations for improved grip and visibility, and tamper-evident screw caps for safe storage. Both the bottle thread and screw cap feature a leakproof design and are made of polypropylene, making them break-resistant and food-safe. The bottles are available in sizes from 125 mL to 2,000 mL.

Purified Exosomes and Dexosomes

System Biosciences' purified exosomes from pooled human biofluid samples come from healthy donors and include exosomes isolated from serum, urine, cerebrospinal fluid, and saliva. Each lot of exosomes is carefully characterized for particle size and concentration by NanoSight analysis, and expression of specific exosome protein markers is validated by Western blot. These exosomes can be used for a variety of applications, including protein biomarker analysis, quantitative PCR for RNA biomarkers, high-throughput biomarker discovery (e.g., mass spectrometry), electron microscopy, and standardized controls for disease studies. Purified exosomes are provided in 1X phosphate buffered saline, and each unit contains 25 µg of exosomal protein. Each vial has enough material to run approximately five lanes in an SDS-PAGE gel (5 µg protein/lane).

Non-Ducted Cabinets

Asynt non-ducted filtration and fume cabinets employ extra-large capacity activated carbon filters for removal of fumes and/or high-efficiency particulate air (HEPA) filters for particulate removal. The filters are up to 30% bigger than that of rival systems and also significantly deeper, making fume removal more efficient and effective, thus delivering improved safety. Providing full compliance with Control of Substances Hazardous to Health (COSHH) regulations, the airflow in the cabinets is constantly monitored and the user alerted by audible and visual alarms should the airflow fall below optimum levels. Asynt will warrant units to be free from defects in materials or workmanship for a period of five years from the date of delivery.

Antibody and Protein Labeling Kit

Lightning-Link enables direct labeling of antibodies or proteins for use in R&D applications, drug discovery, and the development of diagnostic kits. The kits require only 30 s hands-on time and there are no separation steps involved, meaning you will retain 100% of your materials. Simply pipette the antibody or other biomolecule into a vial of lyophilized mixture containing the label of interest and incubate for either 3 h (Lightning-Link range) or only 15 min (Lightning-Link Rapid range). Despite its apparent simplicity, the Lightning-Link process is sophisticated and generates conjugates with performance characteristics identical to, or better than, those prepared with laborious multistep conjugation procedures.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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