Research Article

Transcriptome and epigenome landscape of human cortical development modeled in organoids

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Science  14 Dec 2018:
Vol. 362, Issue 6420, eaat6720
DOI: 10.1126/science.aat6720

Article Information

vol. 362 no. 6420

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  • Received for publication March 30, 2018
  • Accepted for publication November 16, 2018

Author Information

  1. Anahita Amiri1,*,
  2. Gianfilippo Coppola1,*,
  3. Soraya Scuderi1,*,
  4. Feinan Wu1,*,
  5. Tanmoy Roychowdhury2,*,
  6. Fuchen Liu3,
  7. Sirisha Pochareddy3,
  8. Yurae Shin3,4,
  9. Alexias Safi5,
  10. Lingyun Song5,
  11. Ying Zhu3,6,
  12. André M. M. Sousa3,
  13. The PsychENCODE Consortium,
  14. Mark Gerstein7,
  15. Gregory E. Crawford5,
  16. Nenad Sestan3,8,
  17. Alexej Abyzov2,,
  18. Flora M. Vaccarino1,3,8,
  1. Corresponding author: Email: abyzov.alexej{at} (A.A.); flora.vaccarino{at} (F.M.V.)
    1. 1Child Study Center, Yale University, New Haven, CT 06520, USA.
    2. 2Department of Health Sciences Research, Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA.
    3. 3Department of Neuroscience, Yale University, New Haven, CT 06520, USA.
    4. 4National Research Foundation of Korea, Daejeon, South Korea.
    5. 5Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC 27708, USA.
    6. 6Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
    7. 7Department of Molecular Biophysics and Biochemistry, Department of Computer Science, and Department of Statistics and Data Science, Yale University, New haven, CT 06520, USA.
    8. 8Kavli Institute for Neuroscience, Yale University, New Haven, CT 06520, USA.
    1. * These authors contributed equally to this work.

    • The PsychENCODE Consortium authors and affiliations are listed in the supplementary materials.


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