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The runners-up for Science's 2018 Breakthrough of the Year range from the cell—accumulating evidence that minute droplets play critical roles in cellular processes—to the cosmos: the detection of a neutrino from a far-off galaxy. Other advances named by Science are the detection of a massive asteroid impact crater under the Greenland Ice Sheet, a rapid way to derive the molecular structure of tiny crystals, a fossil from the offspring of two genetically distinct archaic humans, gains by the #MeToo movement in science, the use of forensic genealogy to crack unsolved crimes, the detection of fat residues in 500-million-year-old fossils, and the approval of a drug based on the gene-silencing mechanism RNA interference.

  • * Ken Garber is a journalist in Ann Arbor, Michigan.