Contents
08 February 2019
Vol 363, Issue 6427
Vol 363, Issue 6427
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Airport construction threatens Incan heartland
Nearly 200 researchers sign letter opposing project, saying it could harm ancient sites.
- Gut bacteria linked to mental well-being and depression
Microbial biochemistry may affect nerve cell function.
- Indonesian earthquake broke a geologic speed limit
Event could raise hazard risks by showing "supershear" earthquakes can strike more faults.
- Pills give patients a shot inside the stomach
Capsules that internally inject insulin and other medicines could do away with daily jabs.
- Space magnet homes in on dark matter clue
But aging cosmic ray experiment may never explain the mystery of extra antimatter.
- Virtual copy of ransacked museum comes to Mosul
Crowdsourced images allow partial reconstruction of treasures destroyed by the Islamic State group.
Feature
- The new potato
Breeders seek a breakthrough to help farmers facing an uncertain future.
Working Life
Letters
Books et al.
- The end of evolution?
A biochemist's crusade to overturn evolution misrepresents theory and ignores evidence
- Liquid lessons
From ink to oceans, a materials scientist explores the properties of fluids encountered on a transatlantic flight
Policy Forum
- Government data, commercial cloud: Will public access suffer?
New data handling models may affect use for research
Perspectives
- Nitrogen in the environment
Excess nitrogen causes problems in developed nations, but nitrogen-poor soils threaten food security elsewhere
- How do aerosols affect cloudiness?
Cloud-aerosol interactions can be determined more accurately by isolating aerosol effects
- Branched-chain amino acids in disease
Are BCAAs a biomarker, causal agent, or both in cardiometabolic disease?
- A sweeter approach to vaccine design
Glycoengineering may improve next-generation vaccines and immunotherapies
- Slowing blood flow to fight viral infection
T cells produce acetylcholine to dilate blood vessels and migrate into infected tissues
- Single-mode lasing by selective mode pairing
High-order laser modes are suppressed by pairing them with lossy “superpartners”
Research Articles
- Structural basis for blue-green light harvesting and energy dissipation in diatoms
Specialized pigments held together by a protein scaffold help diatoms harvest a broad spectrum of light.
- Aerosol-driven droplet concentrations dominate coverage and water of oceanic low-level clouds
Marine stratocumulus clouds are more sensitive to cloud condensation nuclei than was thought.
- Separating host and microbiome contributions to drug pharmacokinetics and toxicity
Genetic manipulation of drug metabolism in human gut commensal bacteria resolves host and microbiome contributions.
- Eliminating nonradiative decay in Cu(I) emitters: >99% quantum efficiency and microsecond lifetime
Sandwiching copper between redox-active amide and carbene ligands leads to exceptionally efficient photoluminescence.
- Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region
Zika transmission within a Brazilian slum community indicates that prior dengue immunity and local variations influence transmission.
Review
Reports
- An ingestible self-orienting system for oral delivery of macromolecules
An oral device efficiently delivers biomacromolecules via gastric injection.
- Tilting a ground-state reactivity landscape by vibrational strong coupling
Strong coupling of vibrational modes to an optical cavity shifts site-selectivity in competing silyl substitution reactions.
- Dynamic gating of infrared radiation in a textile
A textile composed of carbon nanotube–coated bimorph fibers adapts to the environment and promotes passive cooling.
- Supersymmetric laser arrays
Principles taken from supersymmetry theory are used to design a stable semiconductor laser array.
- Homogenized halides and alkali cation segregation in alloyed organic-inorganic perovskites
Adding alkali metals to lead halide perovskites can spatially homogenize halides and increase charge-carrier lifetimes.
- Life history responses of meerkats to seasonal changes in extreme environments
Seasonal climate changes influence meerkat demographics differently.
- Schema cells in the macaque hippocampus
Primate hippocampal neurons abstract spatial concepts from the environment and encode a schema-like representation of space.
- Choline acetyltransferase–expressing T cells are required to control chronic viral infection
Immunological T cell–derived acetylcholine is required for antiviral immunity.
- Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation
In mice, tumor cells that metastasize to lymph nodes undergo a metabolic shift that can be targeted for therapy.
- Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
Glycosylation may hold the key for designing effective HIV nanoparticle–based vaccines.
Technical Comments
Erratum
From the AAAS Office of Publishing and Member Services
About The Cover
COVER For thousands of years, Andean farmers have cultivated colorful landraces of domesticated potatoes, such as lioness, tunica, and tarmeña shown in this arrangement. Landraces and wild species hold genetic diversity that could be key to developing new potato varieties, which are needed to help farmers adapt to climate change and other challenges. See page 574.
Photo: Gustavo Ramirez