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RENEWAL OF MULTIPLE PRECIPITIN PRODUCTION ON INJECTION OF ONE ANTIGEN IN RABBITS SUCCESSIVELY IMMUNIZED WITH MANY ANTIGENS

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Science  24 Dec 1937:
Vol. 86, Issue 2243, pp. 592-593
DOI: 10.1126/science.86.2243.592

Abstract

Multiple precipitin formation may be induced in the rabbit by the successive introduction of different antigens, and many precipitins may exist simultaneously in the blood for some time. Precipitins no longer demonstrable in the blood of a rabbit subjected to multiple successive immunization may reappear on the injection of only one of the antigens previously injected. Whether an unused antigen would have the same effect has not been determined.