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THE H-ION CONCENTRATION AND THE ORIGIN OF THE HEART BEAT

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Science  21 Feb 1941:
Vol. 93, Issue 2408, pp. 187-188
DOI: 10.1126/science.93.2408.187

Abstract

The rate of the frog or guinea pig heart preparation was not significantly influenced by the H-ion concentration when this was kept within limits which allowed the heart to continue beating. The theory that the H-ion concentration is intimately concerned with the origination of the heart beat is not supported by the results of this investigation.