Technical Comments

Comment on “A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus”

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Science  27 May 2011:
DOI: 10.1126/science.1201399


Wolfe-Simon et al. (Science Express Research Article, published online 2 December 2010; 10.1126/science.1197258) reported that bacterial strain GFAJ-1 can substitute arsenic for phosphorus in its biomolecules, including nucleic acids and proteins. Unfortunately, their study lacks crucial experimental evidence to support this claim and suffers from inadequate data and poor presentation and analysis.