PerspectiveBiochemistry

A Lipid Linchpin for Wnt-Fz Docking

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Science  31 May 2012:
1224468
DOI: 10.1126/science.1224468

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Abstract

The crystal structure of a Wnt-Frizzled complex uncovers an unusual interaction mode, with a lipid in the binding interface holding the complex together.

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