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Conversion of human fibroblasts into functional cardiomyocytes by small molecules

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Science  28 Apr 2016:
aaf1502
DOI: 10.1126/science.aaf1502

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History: 
  • Received for publication December 23, 2015
  • Accepted for publication April 15, 2016

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Author Information

  1. Nan Cao1,2,
  2. Yu Huang1,
  3. Jiashun Zheng4,5,
  4. C. Ian Spencer1,
  5. Yu Zhang1,2,
  6. Ji-Dong Fu6,
  7. Baoming Nie1,2,
  8. Min Xie1,2,
  9. Mingliang Zhang1,2,
  10. Haixia Wang1,2,
  11. Tianhua Ma1,2,
  12. Tao Xu1,2,
  13. Guilai Shi1,2,
  14. Deepak Srivastava1,3,4,*,
  15. Sheng Ding1,2,*,
  1. 1Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
  2. 2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.
  3. 3Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94158, USA.
  4. 4Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
  5. 5California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  6. 6Department of Medicine, Heart and Vascular Research Center, Case Western Reserve University, Cleveland, OH 44106, USA.
  1. Corresponding author. Email: sheng.ding{at}gladstone.ucsf.edu
  1. * These authors contributed equally to this work.

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