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Fibril structure of amyloid-ß(1-42) by cryoelectron microscopy

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Science  07 Sep 2017:
eaao2825
DOI: 10.1126/science.aao2825

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  • Received for publication July 3, 2017
  • Accepted for publication August 24, 2017

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  1. Lothar Gremer1,2,
  2. Daniel Schölzel1,2,
  3. Carla Schenk1,
  4. Elke Reinartz2,
  5. Jörg Labahn1,2,3,
  6. Raimond B. G. Ravelli4,
  7. Markus Tusche1,
  8. Carmen Lopez-Iglesias4,
  9. Wolfgang Hoyer1,2,
  10. Henrike Heise1,2,
  11. Dieter Willbold1,2,*,
  12. Gunnar F. Schröder1,5,*
  1. 1Institute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany.
  2. 2Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.
  3. 3Centre for Structural Systems Biology (CSSB), DESY, 22607 Hamburg, Germany.
  4. 4The Maastricht Multimodal Molecular Imaging Institute, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, Netherlands.
  5. 5Physics Department, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.
  1. *Corresponding author. Email: gu.schroeder{at}fz-juelich.de (G.F.S.); d.willbold{at}fz-juelich.de (D.W.)

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Nov 20171602367450
Dec 2017444111137