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A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

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Science  28 Sep 2017:
eaam7120
DOI: 10.1126/science.aam7120

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History: 
  • Received for publication January 18, 2017
  • Resubmitted May 19, 2017
  • Accepted for publication September 20, 2017

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  1. Ling Yuan1,2,*,
  2. Xing-Yao Huang3,*,
  3. Zhong-Yu Liu3,*,
  4. Feng Zhang1,2,*,
  5. Xing-Liang Zhu1,2,*,
  6. Jiu-Yang Yu3,*,
  7. Xue Ji3,
  8. Yan-Peng Xu3,
  9. Guanghui Li1,2,
  10. Cui Li1,2,
  11. Hong-Jiang Wang3,
  12. Yong-Qiang Deng3,
  13. Menghua Wu4,
  14. Meng-Li Cheng3,5,
  15. Qing Ye3,
  16. Dong-Yang Xie3,5,
  17. Xiao-Feng Li3,
  18. Xiangxi Wang6,
  19. Weifeng Shi7,
  20. Baoyang Hu4,
  21. Pei-Yong Shi8,
  22. Zhiheng Xu1,2,9,,
  23. Cheng-Feng Qin3,
  1. 1State Key Laboratory of Molecular Developmental Biology, CSA Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
  2. 2University of Chinese Academy of Sciences, Beijing 100101, China.
  3. 3Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
  4. 4State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
  5. 5Graduate School, Anhui Medical University, Hefei 230032, China.
  6. 6National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing, 100101, China.
  7. 7Shandong Universities Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases, Taishan Medical College, Taian, 271000, China.
  8. 8Department of Biochemistry and Molecular Biology, Department of Pharmacology and Toxicology, Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
  9. 9Parkinson’s Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China.
  1. Corresponding author. Email: qincf{at}bmi.ac.cn (C.-F.Q.); zhxu{at}genetics.ac.cn (Z.X.)
  1. * These authors contributed equally to this work.

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Sep 20171204125301767
Oct 20171538550075600
Nov 20171177622142983
Dec 20172092996973
Jan 20181285610738
Feb 2018945545725
Mar 20181080485689
Apr 20181021454673
May 2018970518561
Jun 2018796380419
Jul 2018492374387
Aug 20180979478
Sep 20180678520

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