Supplemental Data


Summary
Full Text
Reliability of Protocol Reviews for Animal Research
Scott Plous and Harold Herzog

Supplementary Material


Supplemental Table 1. Description of animal research protocols submitted by IACUCs. Table cells contain frequency of protocols, with parenthetical numbers indicating column percentages within each cell.
Research animal*
Type of protocolCats, dogs, or primatesRatsOther mammalsNonmammalsTotal
Drug or alcohol study
Yes
No
1 (12.5)
7 (87.5)
54 (72.0)
21 (28.0)
11 (32.4)
23 (67.6)
10 (30.3)
23 (69.7)
76 (50.7)
74 (49.3)
Involved surgery
Yes
No
5 (62.5)
3 (37.5)
48 (64.0)
27 (36.0)
6 (17.6)
28 (82.4)
7 (21.2)
26 (78.8)
66 (44.0)
84 (56.0)
Involved food or water deprivation
Yes
No
4 (50.0)
4 (50.0)
24 (32.0)
51 (68.0)
6 (17.6)
28 (82.4)
8 (24.2)
25 (75.8)
42 (28.0)
108 (72.0)
Animals euthanized
Yes
No
5 (62.5)
3 (37.5)
70 (93.3)
5 (6.7)
18 (52.9)
16 (47.1)
15 (45.5)
18 (54.5)
108 (72.0)
42 (28.0)
Main funding was externaldag
Yes
No
4 (50.0)
4 (50.0)
36 (48.0)
39 (52.0)
18 (52.9)
16 (47.1)
14 (42.4)
19 (57.6)
72 (48.0)
78 (52.0)
Approved as written by original IACUC
Yes
No
4 (50.0)
4 (50.0)
30 (40.0)
45 (60.0)
17 (50.0)
17 (50.0)
21 (63.6)
12 (36.4)
72 (48.0)
78 (52.0)
Total number of protocols8753433150
*In one case, a protocol involved both rats and primates (categorized in the table as "primates") and in four cases, protocols involved rats and other mammals (categorized as "other mammals").
dagFunding source as described in protocols.

Supplemental Figure 1. Pain classification scale, adapted from (7).


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