Supplemental Data


Abstract
Full Text
Biodegradable, Elastic Shape Memory Polymers for Potential Biomedical Applications
Andreas Lendlein and Robert Langer

Supplementary Material

Supplemental Table 1. Mechanical properties of the multiblockcopolymers determined by tensile tests at different temperatures.*
Sample IDDagger SymbolT (°C)E (Mpa)Greek Letter SigmaS (Mpa) Greek Letter EpsilonS (%) Greek Letter Sigmamax (Mpa) Greek Letter Epsilonmax (%)
PDC02040 ± 58 ± 133 ± 117 ± 51000 ± 150
PDC92034 ± 89 ± 152 ± 1716 ± 11040 ± 100
PDC192043 ± 69 ± 140 ± 418 ± 2900 ± 100
PDC282039 ± 58 ± 135 ± 121 ± 11100 ± 100
PDC352034 ± 58 ± 149 ± 213 ± 2700 ± 50
PDC642070 ± 1011 ± 137 ± 119 ± 1650 ± 50
PDC832090 ± 3015 ± 241 ± 425 ± 4730 ± 50
PDC03717 ± 22.6 ± 0.124 ± 117 ± 11200 ± 100
PDC93712 ± 32.6 ± 0.333 ± 414 ± 31200 ± 170
PDC193714 ± 52.9 ± 0.433 ± 814 ± 11100 ± 70
PDC283710 ± 32.0 ± 0.432 ± 811 ± 21200 ± 70
PDC353715 ± 32.6 ± 0.536 ± 810 ± 2800 ± 50
PDC643724 ± 35.5 ± 0.135 ± 612 ± 1550 ± 50
PDC833731 ± 46.9 ± 0.137 ± 316 ± 2650 ± 60
PDC0500.2 ± 0.1--0.30 ± 0.051500 ± 200
PDC9500.10 ± 0.03--0.40 ± 0.15800 ± 60
PDC19500.3 ± 0.1--0.5 ± 0.1820 ± 60
PDC28500.9 ± 0.1--0.6 ± 0.1740 ± 60
PDC35502.0 ± 0.6--4.0 ± 0.6560 ± 60
PDC64509.1 ± 1.2--5.9 ± 1.030 ± 10
PDC835016.3 ± 5.7--8.1 ± 1.030 ± 10
*Zwick Z005 with thermo-chamber, deformation rate 10 mm�min-1.
Dagger SymbolThe weight content of oligo(p-dioxanone) in the polymer is given by the two-digit number in the sample ID.

Supplemental Table 2. Thermal properties of the multiblockcopolymers determined by dynamic mechanical analysis at varied temperature* and differential scanning calorimetry.Dagger Symbol
Sample ID Parallel Lines SymbolTg (OCL) *Double Dagger Symbol (°C) Tg (ODX) *Section Symbol (°C) Tg (ODX)Dagger Symbol (°C) Greek Letter DeltacP (ODX Dagger Symbol (J�K�g-1)
PDC0-51 ± 1---
PDC9-51 ± 1-17 ± 1--
PDC19-47 ± 1-15 ± 1-18 ± 20.10 ± 0.01
PDC28-45 ± 2-19 ± 1-24 ± 20.20 ± 0.02
PDC35-46 ± 1-11 ± 1-17 ± 20.13 ± 0.05
PDC64-39 ± 1-4 ± 1-17 ± 20.36 ± 0.01
PDC83-0 ± 1-16 ± 20.60 ± 0.05
*DMTA: Gabo Qualimeter Eplexor, heating from -80°C to 100°C at 2 K�min-1.
Dagger SymbolDSC: Perkin-Elmer DSC 7 at 10 K�min-1, second heating run.
Double Dagger SymbolTemperature at a maximum in E''.
Section SymbolTemperature at a maximum in tan Lowercase Greek Letter Delta.
Parallel Lines Symbol The weight content of oligo(p-dioxanone) in the polymer is given by the two-digit number in the sample ID.


Supplemental Table 3.low = - 20°C and Thigh = 50°C.*
PDC9Dagger Symbol
PDC28Dagger Symbol
PDC35Dagger Symbol
NGreek Letter EpsilonPROG (%)RR (%)RF (%)RR (%)RF (%)RR (%)RF (%)
120076.099.579.099.080.098.0
220089.099.593.599.089.598.0
320099.099.596.099.098.098.0
420099.099.599.099.099.098.0
*Zwick Z005 with thermo-chamber, deformation rate 10 mm�min-1.
Dagger SymbolThe weight content of oligo(p-dioxanone) in the polymer is given by the two-digit number in the sample ID.



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  • Movie 1
    Shape-memory suture changing from a straight to a helical shape when actuated by placing in a water bath at 37°C.

  • Movie 2
    Self-tightening knot: the shape-memory effect is actuated by placing the sample in a water bath at 40°C.