Supporting Online Material
This supplement contains:
Materials and Methods
Figs. S1 and S2
Movies S1 through S4
To view these movies, download a QuickTime viewer.
Supplemental Movies 1 and 2. Cardiac MRI reveals normal heart function in slp-76�/� mice. ECG-gated transverse images were obtained at the level of the papillary muscles and collated to create movie of a wild-type (Supplemental Movie S1) and slp-76�/� (Supplemental Movie S2) heart function during a single cardiac cycle.
Supplemental Movies 3 and 4. First-pass angiography of live wild-type (movie S3) and SLP-76�deficient (movie S4) mice reveals vascular continuity between
blood and lymphatic vessels and early venous filling in SLP-76�deficient animals consistent with shunting. Real-time video
microscopy of the intestinal vasculature was performed after injection of FITC-dextran into the jugular vein. Note the simultaneous
filling of both vein and lymphatic following arterial filling in the SLP-76�deficient animal and the failure of arterial FITC-dextran
to wash out before venous and lymphatic filling.