PT  - JOURNAL ARTICLE
AU  - Norgard, MV
AU  - Miller, JN
TI  - Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria
AID  - 10.1126/science.6264606
DP  - 1981 Jul 31
TA  - Science
PG  - 553--555
VI  - 213
IP  - 4507
4099  - http://science.sciencemag.org/content/213/4507/553.short
4100  - http://science.sciencemag.org/content/213/4507/553.full
SO  - Science1981 Jul 31; 213
AB  - A plasmid DNA structure (approximate molecular weight = 7.5 X 10(6)) was identified in the human pathogen Treponema pallidum (Nichols). The inability to isolate this plasmid from rabbit host tissue and the total lack of DNA homology of the plasmid with rabbit DNA has confirmed its Treponema pallidum origin. The observation documents a newly recognized and potentially significant genetic capability for Treponema pallidum.