Population Size Required for Investigating Threshold Dose in Radiation-Induced Leukemia

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Science  15 May 1959:
Vol. 129, Issue 3359, pp. 1357-1358
DOI: 10.1126/science.129.3359.1357


Studies of leukemia in populations receiving small amounts of radiation are needed to investigate the question of a threshold dose. Estimates have been made of the population sizes required to detect a statistically significant increment of leukemia at specified low exposures, by means of the dose-response relation observed by Court-Brown and Doll at high doses.

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