Respiratory Carbon Dioxide Response Curve Computer

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Science  23 Oct 1959:
Vol. 130, Issue 3382, pp. 1079-1083
DOI: 10.1126/science.130.3382.1079


The respiratory computer described here makes it possible to obtain more accurate and precise alveolar ventilation-PCOCO2 response curves than formerly and with fewer man-hours of labor. It is hoped that the ease of obtaining these response curves will lead to their more frequent use in evaluating respiratory phenomena. Clinical applications in evaluating the effects of changes in compliance and airway resistance on respiration are readily apparent. This technique is being used to study the degree of respiratory depression caused by narcotics and anesthetics and to study the effects of stimulating drugs. Respiratory stimulation and depression in a variety of disease states are also being pursued (13).

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