Adaptation of Cardiac Output to Peripheral Runoff Studied in Intact Dogs

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Science  18 Mar 1960:
Vol. 131, Issue 3403, pp. 828-829
DOI: 10.1126/science.131.3403.828


A pump with sinusoidal piston movement was connected to the abdominal aorta of intact anesthetized dogs, causing slow oscillations of arterial blood pressure. Evidence was found for the existence of a mechanism which enables the heart to adjust its output immediately to changes of peripheral outflow.

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