Effect of 5-Hydroxytryptamine and Iproniazid on Pregnancy

See allHide authors and affiliations

Science  15 Apr 1960:
Vol. 131, Issue 3407, pp. 1101-1102
DOI: 10.1126/science.131.3407.1101


The effects of 5-hydroxytryptamine and iproniazid on pregnancy in mice and rabbits were investigated. 5-Hydroxytryptamine can interrupt pregnancy at all stages in mice but is particularly effective early and late in pregnancy. Iproniazid exerts its action essentially in the first half of pregnancy. 5-Hydroxytryptamine produces striking hemorrhage in the placenta.