Antithyroid Effects of Aminotriazole

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Science  29 Jul 1960:
Vol. 132, Issue 3422, pp. 296-297
DOI: 10.1126/science.132.3422.296


Aminotriazole, Like other antithyroid compounds and low-iodine diets, produces adenomatous changes in the thyroid glands of rats when fed continuously for long periods. Such changes are reversible if the antithyroid regime is discontinued. The antithyroid compounds that are naturally present in food are not regarded as causes of cancer.