Biosynthesis of Chick Hemoglobins

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Science  19 Aug 1960:
Vol. 132, Issue 3425, pp. 468-470
DOI: 10.1126/science.132.3425.468


In vivo studies of the biosynthesis of chick hemoglobins 1 and 2 showed an over-all higher incorporation of glycine-2-C14, valine-4-C14, valine-1-C14, leucine-G-C14, and histidine-(2-ring)-C14 in hemoglobin 2; in vitro studies made with intact nucleated chick erythrocytes showed the higher incorporation of glycine-2-C14, valine-1-C14, and histidine-(2-ring)-C14 in hemoglobin 1. Hybridization of chick hemoglobins produced an electrophoretically distinguishable new component.

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