Transplantation and Malignancy in a Companion-Host System on the Chorioallantoic Membrane

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Science  09 Dec 1960:
Vol. 132, Issue 3441, pp. 1763-1765
DOI: 10.1126/science.132.3441.1763


Pairs of tissue fragments in contact with one another were transplanted onto the chorioallantois. Ten days after transplantation, embryonic lung and liver were found to be accepted, without obvious infiltration of one another. When Walker tumor was substituted for either of the normal tissues, the pair of transplants was also accepted by the chorioallantois, and in addition there was extensive invasive replacement of the normal tissue by the cancer transplant.