Production of Polydipsia in Normal Rats by an Intermittent Food Schedule

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Science  20 Jan 1961:
Vol. 133, Issue 3447, pp. 195-196
DOI: 10.1126/science.133.3447.195


Marked polydipsia was produced in all animals trained to press a bar for food pellets on a 1-minute variableinterval schedule. It is suggested that since this feeding arrangement produces a sustained, high fluid intake in the normal, unrestrained animal, it might serve as a useful tool in the study of renal function.

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