Nature of "Sex-ratio" Agent in Drosophila

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Science  12 May 1961:
Vol. 133, Issue 3463, pp. 1489-1490
DOI: 10.1126/science.133.3463.1489


Several lines of evidence implicate small spirochetes, presumably treponemata, as etiologic agents in the production of the maternally transmitted "sex ratio" condition (SR) in Drosophila nebulosa, in D. willistoni, and in strains of D. melanogaster into which the SR condition has been artificially transferred. The presence of treponemata in the hemolymph of adult females of these species is completely correlated with the production of unisexual progenies and like this condition is dependent on the genotype of the host and of the infectious agent.

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