Response of the Neotenic Salamander Haideotriton wallacei to a Metamorphic Agent

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Science  23 Mar 1962:
Vol. 135, Issue 3508, pp. 1060-1061
DOI: 10.1126/science.135.3508.1060


The neotenic, cave-dwelling plethodontid salamander Haideotriton wallacei undergoes only a few minor integumentary changes and loses only a single bone, the coronoid, when treated with sodium laevo thyroxin. Since neither the animal's thyroid nor the supplementary thyroxin is sufficient to effect substantial metamorphosis, genetic factors probably restrict the animal's ability to transform.