Strain and Sex Differences in Serum Cholesterol Levels of Mice

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Science  23 Mar 1962:
Vol. 135, Issue 3508, pp. 1071-1072
DOI: 10.1126/science.135.3508.1071


Five inbred strains of mice differed significantly in serum cholesterol level. Cholesterol levels ranged from 128 mg/100 ml in C57B1/6 mice to 208 mg/100 ml in C3H mice. Cholesterol level was significantly higher in males than in females. The cholesterol level of 2-month-old mice did not differ from that of 1-year-old mice.