Carbon Dioxide Fixation in Lobster Nerve

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Science  01 Jun 1962:
Vol. 136, Issue 3518, pp. 782-783
DOI: 10.1126/science.136.3518.782-a


Aspartic, glutamic, malic, and citric (isocitric) acids were isolated by chromatographic methods from lobster nerves incubated with Ringer's solution containing C14-bicarbonate. All the compounds were labeled; the bulk of the radioactivity appeared in the aspartic acid. The findings suggest the operation in lobster nerves of the citric acid cycle including CO2 fixation.

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