Synthesis of Chicken Antibodies of High and Low Molecular Weight

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Science  29 Mar 1963:
Vol. 139, Issue 3561, pp. 1302-1303
DOI: 10.1126/science.139.3561.1302


Two major populations of chicken macroglobulin antibodies in primary- and secondary-response serums are associated with electrophoretically slow- and fast-moving γ-globulins. If the fractions separable by electrophoresis are treated with 2-mercaptoethanol, two populations of 7S antibodies are revealed. Primary-response precipitins have the characteristics of macroglobulins.