Hypoglycemia: A Potent Stimulus to Secretion of Growth Hormone

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Science  31 May 1963:
Vol. 140, Issue 3570, pp. 987-988
DOI: 10.1126/science.140.3570.987


In normal subjects, hypoglycemia produces an abrupt and sustained rise in levels of human growth hormone in plasma. This effect is independent of insulin, glucagon, or epinephrine. Prolonged fasting is accompanied by a rise in the hormone level in plasma. Measurement of this hormone after induced hypoglycemia is a specific test for pituitary somatotropic function.

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