Antibody Combining Site: The B Polypeptide Chain

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Science  23 Aug 1963:
Vol. 141, Issue 3582, pp. 726-727
DOI: 10.1126/science.141.3582.726


The antibody molecule consists of several polypeptide chains. Peptides, which appear to have been derived from the binding region of the rabbitantibody molecule directed against pazobenzenearsonate, have been isolated. The particular polypeptide chain from which these peptides are derived has now been identified as the B chain described by Fleischman, Pain, and Porter.