Antigenic Histamine Release from Passively Sensitized Human Leukocytes

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Science  20 Sep 1963:
Vol. 141, Issue 3586, pp. 1190-1191
DOI: 10.1126/science.141.3586.1190


With histamine release as an indicator, consistent passive sensitization of normal human leukocytes to specific anligen could be achieved with human serum, fresh or stored at -70 ° C, from allergic individuals. With certain sera, dilution slowed the rate of sensitization but increased eventual histamine release.

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