Drug Administration to Neonatal Rats: Effects on Later Emotionality and Learning

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Science  06 Mar 1964:
Vol. 143, Issue 3610, pp. 1055-1057
DOI: 10.1126/science.143.3610.1055


The effects of extra stimulation during postnatal days 2 to 4 in rats are mitigated by the injection of either norepinephrine or chlorpromazine prior to the stimulation. Behavioral changes in locomotion and defecation occurred in the open field, and there were changes in speed and accuracy of learning a simple maze problem.