Simultaneous Studies of Firing Patterns in Several Neurons

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Science  20 Mar 1964:
Vol. 143, Issue 3612, pp. 1325-1327
DOI: 10.1126/science.143.3612.1325


A tungsten microelectrode with several small holes burnt in the vinyl insulation enables the action potentials from several adjacent neurons to be observed simultaneously. A digital computer is used to separate the contributions of each neuron by examining and classifying the waveforms of the action potentials. These methods allow studies to be made of interactions between neurons that lie close together.