DNA from Bacteriophage Lambda: Molecular Length and Conformation

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Science  29 May 1964:
Vol. 144, Issue 3622, pp. 1142-1144
DOI: 10.1126/science.144.3622.1142


The length of the DNA molecules from wild-type λ bacteriophage is 17.2 µ, corresponding to a molecular weight of 33 million in the B form. The molecules from a double-deletion mutant of λ are 23 percent shorter. Both types of molecules join ends at 60°C to form circular molecules or polymers. The point of junction cannot be distinguished by any irregularity in the uniform duplex molecule.

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