Ostracitoxin: An Ichthyotoxic Stress Secretion of the Boxfish, Ostracion lentiginosus

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Science  09 Oct 1964:
Vol. 146, Issue 3641, pp. 244-245
DOI: 10.1126/science.146.3641.244


Boxfish under stress produce an ichthyotoxic, hemolytic, nonprotein poison in the mucous secretions of their skin. This heat-stable, nondialyzable "ostracitoxin" foams profusely in aqueous solutions and is toxic to various biological systems. It is apparently unique among known fish poisons; it is toxic to boxfish and resembles red tide and sea cucumber toxins in general properties.

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