Synergism between a Lactate Dehydrogenase-Elevating Virus and Eperythrozoon coccoides

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Science  13 Nov 1964:
Vol. 146, Issue 3646, pp. 921-923
DOI: 10.1126/science.146.3646.921


An interaction occurs when a lactate dehydrogenase-elevating virus and Eperythrozoon coccoides are present together in the mouse host. The synergism is expressed by a substantial increase in plasma lactate dehydrogenase, spleen enlargement, host anemia, and quantitative alteration of several blood elements.