Epidermal Papillomas with Virus-like Particles in Flathead Sole, Hippoglossoides elassodon

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Science  13 Nov 1964:
Vol. 146, Issue 3646, pp. 932-934
DOI: 10.1126/science.146.3646.932


Epidermal papillomas frequently occur on the external surfaces of flathead sole, Hippoglossoides elassodon, in the waters of San Juan Islands, Washington. Virus-like particles and associated granular bodies, also of possible viral nature, are commnonly found in the neoplastic epithelial cells of these tumors. Similar structures are not observed in normal epidermis.