Immunity and Susceptibility toward Cheek Pouch Transplants of a Mouse Leukemia

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Science  13 Nov 1964:
Vol. 146, Issue 3646, pp. 944-945
DOI: 10.1126/science.146.3646.944


Intravenous sensitization with spleen or leukemic cells of mice and certain rats immunized Syrian hamsters toward cheek pouch heterografts of a mouse leukemia. By contrast, sensitized hamsters given cortisone became more susceptible to the challenging leukemic graft. Neither response was elicited by sensitization with cells of the guinea pig, Syrian hamster, rabbit, or human being.