Nuclear Magnetic Resonance Studies of Living Muscle

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Science  12 Feb 1965:
Vol. 147, Issue 3659, pp. 738-739
DOI: 10.1126/science.147.3659.738


Measurements of nuclear magnetic relaxation times for protons of water in living skeletal frog muscle show the transverse relaxation time, T2, increases when a muscle contracts isometrically. This result and other experimental data suggest that a fraction of the intracellular water molecules have restricted rotational freedom and that this fraction decreases when contraction occurs.

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