Micropuncture Study of Inulin Absorption in the Rat Kidney

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Science  12 Feb 1965:
Vol. 147, Issue 3659, pp. 753-754
DOI: 10.1126/science.147.3659.753


By means of a microinjection technique, inulin-carboxyl-C14 or inulin-methoxy-H3 was injected into single proximal tubules of the rat at various urine flow rates. Urine collected separately from the two kidneys showed negligible amounts of inulin activity on the noninjected side, thus demonstrating directly that there is no significant reabsorption of inulin by the renal tubular epithelium under these conditions.

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