Complexes of F-Pili and RNA Bacteriophage

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Science  23 Apr 1965:
Vol. 148, Issue 3669, pp. 511-513
DOI: 10.1126/science.148.3669.511


Cell-free filtrates of F+ strains of Escherichia coli "inactivate" RNA phages. The active agents have been identified in the electron microscope as thin appendages called F-pili. Complexes of F-pili and phage may be easily assayed because of their retention by membrane filter pads. Calcium ion is required for formation of the complex.