Lysis of Pleuropneumonia-like Organisms by Staphylococcal and Streptococcal Toxins

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Science  28 May 1965:
Vol. 148, Issue 3674, pp. 1229-1231
DOI: 10.1126/science.148.3674.1229


Six strains representing three species of Mycoplasma were examined for susceptibility to lysis by staphylococcal and streptococcal toxins. All were sensitive to staphylococcal α-toxin, two to streptolysin S, and three to streptolysin O. The results support the concept that the limiting membrane of pleuropneumonia-like organisms is basically similar to those of many other cell types and provide additional evidence for the participation of cholesterol in cytolysis induced by streptolysin O.