Alcohol Dehydrogenase in Drosophila melanogaster: Isozymes and Genetic Variants

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Science  02 Jul 1965:
Vol. 149, Issue 3679, pp. 80-82
DOI: 10.1126/science.149.3679.80


Alcohol dehydrogenase, in Drosophila melanogaster homozygous for the alleles AdhF or AdhS, is found in three electrophoretically different forms. Adh' differs from Adh5 in that isozymes with faster electrophoretic mobilities are present. In AdhF/AdhS heterozygotes, hybrid isozymes as well as the parental isozymes are present, indicating that the dehydrogenase may exist as a dimer of two polypeptide subunits. The gene, Adh, is located on the second chromosome, with a map position of 50.1 and a cytological position between 34E3 and 35D1.