Adenovirus-Associated Defective Virus Particles

See allHide authors and affiliations

Science  13 Aug 1965:
Vol. 149, Issue 3685, pp. 754-755
DOI: 10.1126/science.149.3685.754


Small, DNA-containing particles were separated from preparations of a simian adenovirus. These particles differed antigenically from the adenovirus. Replication of the particles in cell cultures was obtained only when theywere inoculated simultaneously with adenoviruses. This suggests that these adenovirus-associated particles behave as defective viruses.

Stay Connected to Science