Triploidy in a Human Cell Line

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Science  24 Sep 1965:
Vol. 149, Issue 3691, pp. 1516-1517
DOI: 10.1126/science.149.3691.1516


Cytogenetic studies of a human amnion cell line (strain RA) indicate that the major stem cell was triploid. Consistently present in the triploid cells were two marker chromosomes, a small centric fragment, and an apparently telocentric D. At various times triploid cells constituted 40 to 80 percent of the cell population. The possible origin of the triplaid cell is a diploid/ triploid mosaic amnion.