Electron Microscopic Autoradiography of Rabbit Reticulocytes Active and Inactive in Protein Synthesis

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Science  25 Feb 1966:
Vol. 151, Issue 3713, pp. 1000-1001
DOI: 10.1126/science.151.3713.1000


Electron microscopic autoradiography indicates that only a fraction of ribosome-containing reticulocytes (from phenylhydrazine-treated rabbits) is capable of active protein synthesis in vitro. Ribosomes, and, indeed, polyribosomes, do not appear to limit the rate of protein synthesis.